≡

Acyl Carrier Protein, Mitochondrial (ACP)

[Edit]

NDUFAB1; CI-SDAP; SDAP; FASN2A; NADH-Ubiquinone Oxidoreductase 9.6 kDa Subunit

Acyl Carrier Protein, Mitochondrial (ACP)
CCC A361
HGNC 7694
MGI 1917566
PubMed 8016262
RGD 1305619
UniProt O14561
The acyl carrier protein (ACP) is an important component in both fatty acid and polyketide biosynthesis with the growing chain bound during synthesis as a thiol ester at the distal thiol of a 4'-phosphopantethiene moiety. The protein is expressed in the inactive apo form and the 4'-phosphopantetheine moiety must be post-translationally attached to a conserved serine residue on the ACP by the action of holo-acyl carrier protein synthase (ACPS) a phosphopantetheinyl transferase.The multisubunit NADH:ubiquinone oxidoreductase (complex I) is the first enzyme complex in the electron transport chain of mitochondria.Runswick et al. (1991) reported that the bovine SDAP subunit of complex I is an acyl carrier protein. Loeffen et al. (1998) stated that GenBank represents the cDNA encoding the human homolog of SDAP.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA361Hu01 Recombinant Acyl Carrier Protein, Mitochondrial (ACP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA361Hu01 Polyclonal Antibody to Acyl Carrier Protein, Mitochondrial (ACP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Acyl Carrier Protein, Mitochondrial (ACP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Carrier Protein, Mitochondrial (ACP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA361Mu01 Recombinant Acyl Carrier Protein, Mitochondrial (ACP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA361Mu01 Polyclonal Antibody to Acyl Carrier Protein, Mitochondrial (ACP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Acyl Carrier Protein, Mitochondrial (ACP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Carrier Protein, Mitochondrial (ACP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acyl Carrier Protein, Mitochondrial (ACP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acyl Carrier Protein, Mitochondrial (ACP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Carrier Protein, Mitochondrial (ACP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Carrier Protein, Mitochondrial (ACP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Carrier Protein, Mitochondrial (ACP) ELISA Kit Customized Service Offer
  1. "cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed."Biochem. Biophys. Res. Commun. 253:415-422(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."Genomics 60:295-308(1999) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini."Proc. Natl. Acad. Sci. U.S.A. 106:19310-19315(2009) [PubMed] [Europe PMC] [Abstract]
  6. "The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification."J. Biol. Chem. 278:13619-13622(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Solution structure of RSGI RUH-059, an ACP domain of acyl carrier protein, mitochondrial from human."Submitted (OCT-2006) to the PDB data bank