![GATA Binding Protein 5 (GATA5)](/upload/item/img/GATA-Binding-Protein-5-(GATA5)-90342.jpg)
Transcription factor GATA-5 is is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
GATA5 Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GATA Binding Protein 5 (GATA5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEA342Hu | ELISA Kit for GATA Binding Protein 5 (GATA5) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA342Mu01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to GATA Binding Protein 5 (GATA5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GATA Binding Protein 5 (GATA5) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA342Ra01 | Recombinant GATA Binding Protein 5 (GATA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA342Ra01 | Polyclonal Antibody to GATA Binding Protein 5 (GATA5) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for GATA Binding Protein 5 (GATA5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GATA Binding Protein 5 (GATA5) | ELISA Kit Customized Service Offer |
- "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation."Clinics (Sao Paulo) 67:1393-1399(2012) [PubMed] [Europe PMC] [Abstract]
- "Mutational spectrum of the GATA5 gene associated with familial atrial fibrillation."Int. J. Cardiol. 157:305-307(2012) [PubMed] [Europe PMC] [Abstract]
- "Rare non-synonymous variations in the transcriptional activation domains of GATA5 in bicuspid aortic valve disease."J. Mol. Cell. Cardiol. 53:277-281(2012) [PubMed] [Europe PMC] [Abstract]
- "GATA5 loss-of-function mutations underlie tetralogy of fallot."Int. J. Med. Sci. 10:34-42(2013) [PubMed] [Europe PMC] [Abstract]
- "A novel GATA5 loss-of-function mutation underlies lone atrial fibrillation."Int. J. Mol. Med. 31:43-50(2013) [PubMed] [Europe PMC] [Abstract]
- "GATA5 loss-of-function mutation responsible for the congenital ventriculoseptal defect."Pediatr. Cardiol. 34:504-511(2013) [PubMed] [Europe PMC] [Abstract]
- "GATA5 loss-of-function mutations associated with congenital bicuspid aortic valve."Int. J. Mol. Med. 33:1219-1226(2014) [PubMed] [Europe PMC] [Abstract]
- "Somatic GATA5 mutations in sporadic tetralogy of Fallot."Int. J. Mol. Med. 33:1227-1235(2014) [PubMed] [Europe PMC] [Abstract]
- "GATA5 loss-of-function mutation in familial dilated cardiomyopathy."Int. J. Mol. Med. 35:763-770(2015) [PubMed] [Europe PMC] [Abstract]