Latrophilin 3 (LPHN3)
[Edit]CIRL3; LEC3; Calcium-independent alpha-latrotoxin receptor 3; Lectomedin-3
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Latrophilin-3 is a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.
Latrophilin 3forms a heterodimer, consisting of a large extracellular region (p120) non-covalently linked to a seven-transmembrane moiety (p85)
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA340Hu01 | Recombinant Latrophilin 3 (LPHN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA340Hu01 | Polyclonal Antibody to Latrophilin 3 (LPHN3) | WB; IHC |
| MAA340Hu22 | Monoclonal Antibody to Latrophilin 3 (LPHN3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA340Hu | ELISA Kit for Latrophilin 3 (LPHN3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Latrophilin 3 (LPHN3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Latrophilin 3 (LPHN3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Latrophilin 3 (LPHN3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Latrophilin 3 (LPHN3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Latrophilin 3 (LPHN3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Latrophilin 3 (LPHN3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Latrophilin 3 (LPHN3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Latrophilin 3 (LPHN3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Latrophilin 3 (LPHN3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Latrophilin 3 (LPHN3) | ELISA Kit Customized Service Offer |
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]
- "Screening of human LPHN3 for variants with a potential impact on ADHD susceptibility."Am. J. Med. Genet. B Neuropsychiatr. Genet. 156:11-18(2011) [PubMed] [Europe PMC] [Abstract]