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Microtubule Associated Protein 1A (MAP1A)

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MAP-1A; MAP1-A; MAP1L; MTAP1A; Proliferation-related protein p80

Microtubule Associated Protein 1A (MAP1A)
CCC A338
HGNC 6835
MGI 1306776
PubMed 11896150
RGD 3042
UniProt P78559
Wiki MAP1A
These proteins have been divided into 2 main groups by molecular mass, high molecular weight MAPs, which include MAP1A, MAP1B, and MAP2, and another group of intermediate-sized proteins, which include the abundant tau MAPs. MAP1B, also named MAP5, is a component of long cross-bridges between microtubules and is a filamentous molecule with a small spherical segment at one end.
Lien et al. (1994) completely cloned and sequenced the human MAP1B gene. By comparison of human MAP1B with sequence databases, they identified a MAP1B-related gene that is probably the human homolog of rat MAP1A. The human MAP1A gene is expressed at high levels in brain and spinal cord and at much lower levels in muscle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Microtubule Associated Protein 1A (MAP1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Microtubule Associated Protein 1A (MAP1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Microtubule Associated Protein 1A (MAP1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Microtubule Associated Protein 1A (MAP1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Microtubule Associated Protein 1A (MAP1A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA338Mu01 Recombinant Microtubule Associated Protein 1A (MAP1A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA338Mu01 Polyclonal Antibody to Microtubule Associated Protein 1A (MAP1A) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Microtubule Associated Protein 1A (MAP1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Microtubule Associated Protein 1A (MAP1A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA338Ra01 Recombinant Microtubule Associated Protein 1A (MAP1A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA338Ra01 Polyclonal Antibody to Microtubule Associated Protein 1A (MAP1A) WB; IHC; ICC; IP.
Assay Kits SEA338Ra ELISA Kit for Microtubule Associated Protein 1A (MAP1A) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Human microtubule-associated protein 1a (MAP1A) gene: genomic organization, cDNA sequence, and developmental- and tissue-specific expression."Genomics 35:577-585(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  3. "Brain-specific expression of human microtubule-associated protein 1A (MAP1A) gene and its assignment to human chromosome 15."J. Neurosci. Res. 40:820-825(1995) [PubMed] [Europe PMC] [Abstract]
  4. "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  8. "MAP1 structural organization in Drosophila: in vivo analysis of FUTSCH reveals heavy- and light-chain subunits generated by proteolytic processing at a conserved cleavage site."Biochem. J. 414:63-71(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]