Neuronal Pentraxin II (NPTX2)

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NARP2; NP-II; NP2; Apexin

Neuronal Pentraxin II (NPTX2)
Neuronal pentraxin 2 been identified by Hsu and Perin. It is related to a secreted member of the pentraxin family identified first in rats, termed NPTX1. Unlike NPTX1, which is expressed almost exclusively in neuronal tissues, NPTX2 is expressed in brain, testis, pancreas, liver, heart, and skeletal muscle. The protein is also being referred to as NARP, a secreted protein with features of a calcium dependent lectin, which acts as a neurotrophic factor promoting neuronal migration and dendritic outgrowth of neurons with the same potency as neurotrophins and growth factors . Reti et al have localized NARP in vasopressin neurons of the hypothalamus and in the posterior pituitary. Several stimuli known to trigger vasopressin release, i.,e., hypovolemia, dehydration, and endotoxin, elevate plasma Narp levels.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA299Hu01 Recombinant Neuronal Pentraxin II (NPTX2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA299Hu01 Polyclonal Antibody to Neuronal Pentraxin II (NPTX2) WB; IHC; ICC; IP.
MAA299Hu22 Monoclonal Antibody to Neuronal Pentraxin II (NPTX2) WB; IHC; ICC; IP.
MAA299Hu21 Monoclonal Antibody to Neuronal Pentraxin II (NPTX2) WB; IHC; ICC; IP.
Assay Kits SEA299Hu ELISA Kit for Neuronal Pentraxin II (NPTX2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuronal Pentraxin II (NPTX2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuronal Pentraxin II (NPTX2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuronal Pentraxin II (NPTX2) Polyclonal Antibody Customized Service Offer
Assay Kits SEA299Mu ELISA Kit for Neuronal Pentraxin II (NPTX2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA299Ra01 Recombinant Neuronal Pentraxin II (NPTX2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA299Ra01 Polyclonal Antibody to Neuronal Pentraxin II (NPTX2) WB; IHC; ICC; IP.
MAA299Ra21 Monoclonal Antibody to Neuronal Pentraxin II (NPTX2) WB; IHC; ICC; IP.
Assay Kits SEA299Ra ELISA Kit for Neuronal Pentraxin II (NPTX2) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Human neuronal pentraxin II (NPTX2): conservation, genomic structure, and chromosomal localization."Genomics 28:220-227(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2."J. Biol. Chem. 275:17786-17792(2000) [PubMed] [Europe PMC] [Abstract]