![Centromere Protein E (CENPE)](/upload/item/img/Centromere-Protein-E-(CENPE)-90276.jpg)
CENP-E is a large protein of ∼312 kDa consisting of an NH2-terminal kinesin motor domain tethered to a globular COOH-terminal domain via an extended “rod” domain predicted to form a coiled coil. Kinesin motors hydrolyze ATP to produce directed mechanical force along microtubules. In the case of CENP-E, the motor activity is involved in establishing and maintaining stable connections between mitotic chromosomes and the microtubules of the mitotic spindle. CENP-E exhibits a periodic accumulation and loss, with maximal levels found during late G2 and M-phases of the cell cycle, and minimum levels in early G1. CENP-E is thus appropriately spatially and temporally positioned to integrate the regulation of the mitotic checkpoint with the mechanics of chromosome-microtubule interactions.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA276Hu01 | Recombinant Centromere Protein E (CENPE) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA276Hu01 | Polyclonal Antibody to Centromere Protein E (CENPE) | WB; IHC; ICC; IP. |
MAA276Hu21 | Monoclonal Antibody to Centromere Protein E (CENPE) | WB; IHC; ICC; IP. | |
Assay Kits | SEA276Hu | ELISA Kit for Centromere Protein E (CENPE) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Centromere Protein E (CENPE) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Centromere Protein E (CENPE) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Centromere Protein E (CENPE) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Centromere Protein E (CENPE) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Centromere Protein E (CENPE) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA276Ra01 | Recombinant Centromere Protein E (CENPE) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA276Ra01 | Polyclonal Antibody to Centromere Protein E (CENPE) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Centromere Protein E (CENPE) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Centromere Protein E (CENPE) | ELISA Kit Customized Service Offer |
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