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Caspase 2 (CASP2)

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ICH1L; NEDD2; ICH-1L/1S; Cysteinyl Aspartate Specific Proteinases 2; Apoptosis-Related Cysteine Peptidase; Neural Precursor Cell Expressed Developmentally Down-Regulated 2

Caspase 2 (CASP2)
CCC A244
HGNC 1503
MGI 97295
PubMed 12065594
RGD 69274
UniProt P42575
Wiki Caspase_2

Caspase 2 proteolytically cleaves other proteins. It belongs to a family of cysteine proteases called caspases that only cleave proteins at an amino acid following a aspartic acid residue. Within this family, caspase 2 is part of the Ich-1 subfamily. It is one of the most conserved caspases in different species of animal. Caspase 2 has a similar amino acid sequence to initiator caspases, including caspase 1, caspase 4, caspase 5 and caspase 9. It is produced as a zymogen, which contains a long pro-domain that is similar to that of caspase 9 and contains a protein interaction domain known as a CARD domain. Pro-caspase-2 contains two subunits, p19 and p12.In addition, caspase 2 may form a complex with the catalytic subunit of DNA-PK (DNA-PKcs) and PIDD (LRDD), which is involved in DNA repair after DNA damage.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA244Hu01 Recombinant Caspase 2 (CASP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA244Hu02 Recombinant Caspase 2 (CASP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA244Hu03 Recombinant Caspase 2 (CASP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA244Hu04 Recombinant Caspase 2 (CASP2) Positive Control; Immunogen; SDS-PAGE; WB.
APA244Hu04 Active Caspase 2 (CASP2) Cell culture; Activity Assays.
Antibodies PAA244Hu01 Polyclonal Antibody to Caspase 2 (CASP2) WB; IHC; ICC; IP.
LAA244Hu71 Biotin-Linked Polyclonal Antibody to Caspase 2 (CASP2) WB; IHC; ICC.
LAA244Hu81 FITC-Linked Polyclonal Antibody to Caspase 2 (CASP2) WB; IHC; ICC; IF.
PAA244Hu02 Polyclonal Antibody to Caspase 2 (CASP2) WB,IHC,ICC/IF
Assay Kits SEA244Hu ELISA Kit for Caspase 2 (CASP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA244Mu01 Recombinant Caspase 2 (CASP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA244Mu02 Recombinant Caspase 2 (CASP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA244Mu01 Polyclonal Antibody to Caspase 2 (CASP2) WB; IHC; ICC; IP.
PAA244Mu02 Polyclonal Antibody to Caspase 2 (CASP2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Caspase 2 (CASP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Caspase 2 (CASP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Caspase 2 (CASP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Caspase 2 (CASP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Caspase 2 (CASP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Caspase 2 (CASP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Caspase 2 (CASP2) ELISA Kit Customized Service Offer
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