Pepsinogen C (PGC)

Pepsinogen, the inactive precursor of pepsin belongs to the group of aspartic proteinases, is synthesized in the chief cells of gastric glands. Seven electrophoretically separable pepsinogens exist in human gastric mucosa. One group, called PGA or group I pepsinogen, is characterized by electrophoretically faster migration and localization in the fundus and body of the stomach; the second group, termed pepsinogen C, is localized in the whole stomach. PGCs are found in prostate and in seminal fluid whereas PGAs are not. the absence of detectable immunologic crossreactivity between the pepsinogens A and C results from divergent evolution of sequences located on the surface of the zymogens in contrast to the strongly conserved active site regions located within the binding cleft of the enzymes, inaccessible for antigenic recognition.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA166Hu01 Recombinant Pepsinogen C (PGC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA166Hu01 Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IP; FCM
MAA166Hu22 Monoclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IP.
LAA166Hu71 Biotin-Linked Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC.
LAA166Hu81 FITC-Linked Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IF.
Assay Kits SEA166Hu ELISA Kit for Pepsinogen C (PGC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA166Mu01 Recombinant Pepsinogen C (PGC) Positive Control; Immunogen; SDS-PAGE; WB.
RPA166Mu02 Recombinant Pepsinogen C (PGC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA166Mu01 Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IP.
PAA166Mu02 Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IP.
Assay Kits SEA166Mu ELISA Kit for Pepsinogen C (PGC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA166Ra01 Recombinant Pepsinogen C (PGC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA166Ra01 Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IP.
MAA166Ra22 Monoclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IP.
LAA166Ra71 Biotin-Linked Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC.
LAA166Ra81 FITC-Linked Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IF.
Assay Kits SEA166Ra ELISA Kit for Pepsinogen C (PGC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA166Ga01 Recombinant Pepsinogen C (PGC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA166Ga01 Polyclonal Antibody to Pepsinogen C (PGC) WB; IHC; ICC; IP.
Assay Kits SEA166Ga ELISA Kit for Pepsinogen C (PGC) Enzyme-linked immunosorbent assay for Antigen Detection.
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  2. ErratumJ. Biol. Chem. 263:14592-14592(1988)
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