Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF)
[Edit]CSF2; GMCSF; Sargramostim; Molgramostin; Granulocyte-Macrophage Colony Stimulating Factor
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Granulocyte-macrophage colony stimulating factor (GM-CSF) was initially identified by its ability to stimulate the formation of granulocyte and macrophage colonies from hematopoietic progenitor cells in semi-solid media. In vivoand in vitro studies have now demonstrated that GM-CSF is a pleiotropic cytokine that induces myeloid precursor cells to proliferate and differentiate into neutrophils, monocyte/macrophages and eosinophils.
GM-CSF has also been shown to stimulate the proliferation and differentiation of erythroid and megakaryocyte progenitor cells. In addition, GM-CSF is a survival factor for and activates the effector functions of mature neutrophils, monocytes/macrophages and eosinophils.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA045Ca01 | Recombinant Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA045Ca01 | Polyclonal Antibody to Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | WB; IHC; ICC; IP. |
| MAA045Ca21 | Monoclonal Antibody to Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA045Ca | ELISA Kit for Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA045Ca | CLIA Kit for Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA045Po01 | Recombinant Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEA045Po | ELISA Kit for Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Ovis aries; Ovine (Sheep)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA045Ov01 | Recombinant Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA045Ov01 | Active Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Cell culture; Activity Assays. | |
| Antibodies | n/a | Monoclonal Antibody to Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF) | ELISA Kit Customized Service Offer |
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- "The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation."Cell 134:496-507(2008) [PubMed] [Europe PMC] [Abstract]