Monoclonal Antibody to Selenoprotein P1, Plasma (SEPP1)

SEPP; SeP; SEP-P1; SELP

SPECIFITY

The antibody is a mouse monoclonal antibody raised against SEPP1. It has been selected for its ability to recognize SEPP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
The Journal of Clinical Endocrinology & Metabolism Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and Atherosclerosis PubMed: 21677040
Diabetes & metabolism journal Increased Selenoprotein P Levels in Subjects with Visceral Obesity and Nonalcoholic Fatty Liver Disease PubMed: 23439771
Journal of Pediatric Biochemistry Trace elements, heavy metals and vitamins in Egyptian school children with iron deficiency anemia Metapress:Source
Journal of Trace Elements in Medicine and Biology Selenium and its relationship with selenoprotein P and glutathione peroxidase in children and adolescents with Hashimoto's thyroiditis and hypothyroidism PubMed: 26854239
OBES RES CLIN PRACT/OBESITY RESEARCH & CLINICAL PRACTICE Selenoprotein P is elevated in individuals with obesity, but is not independently associated withinsulin resistance. pubmed:27524654
Annals of Nutrition and Metabolism Acute Overfeeding Does Not Alter Liver or Adipose Tissue-Derived Cytokines in HealthyHumans. pubmed:27832637
European Journal of Nutrition DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: ashort-term supplementation trial with respect to GPX1 and SEPP1 polymorphism. pubmed:26658762
South. Clin. Ist. Euras. Evaluation of the Relationship Between Insulin Resistance and Selenoprotein P in Patients with Polycystic Ovary Syndrome DOI: 10.14744/scie.2017.87597
Arch Endocrinol Metab Serum selenium and selenoprotein-P levels in autoimmune thyroid dieases patients in a select center a transversal study DOI: 10.1590/2359-3997000000309
British Journal of Nutrition Selenium, selenoproteins and selenometabolites in mothers and babies at the time of birth pubmed:28534447
Journal of Trace Elements in Medicine and Biology Biomarkers of selenium status and antioxidant effect in workers occupationally exposed to mercury Pubmed:29895371
Biological & Pharmceutical Bulletin Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits Pubmed:29709922
Diabetologia Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus Pubmed: 30470912
Biological Trace Element Research Selenium Levels in Community Dwellers with Type 2 Diabetes Mellitus Pubmed: 30725267
Advances in Medical Sciences Can hepatokines be regarded as novel non-invasive serum biomarkers of intrahepatic lipid content in obese children? Pubmed: 30921653
Acute swimming exercise, but not exposure to moderate hypoxic conditions reduces circulating selenoprotein P levels in short-term, high-fat diet-fed rats Pubmed: 31236416
Hormones Selenium and selenoprotein P in nonalcoholic fatty liver disease Pubmed: 31493247
Bull Environ Contam Toxicol Soil Selenium Concentration and Residents Daily Dietary Intake in a Selenosis Area: A Preliminary Study in Yutangba Village, Enshi City, China Pubmed: 32909074
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Higher Serum Selenoprotein P Level as a Novel Inductor of Metabolic Complications in Psoriasis Pubmed: 32605214
Circulating hepassocin level in patients with stable angina is associated with fatty liver and renal function
Nat Immunol Selenium–GPX4 axis protects follicular helper T cells from ferroptosis 34413521
Reviews in Cardiovascular Medicine Selenoprotein P-1 (SEPP1) as An Early Biomarker of Acute Kidney Injury in Patients Undergoing Cardiopulmonary Bypass
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