Beta-2-Microglobulin (b2M)

β2 microglobulin lies lateral to the α3 chain on the cell surface. Unlike α3, β2 has no transmembrane region. Directly above β2 lies the α1 chain, which itself is lateral to the α2. β2 microglobulin associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa.

An additional function is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis.

 

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA260Hu01 Recombinant Beta-2-Microglobulin (b2M) Positive Control; Immunogen; SDS-PAGE; WB.
EPA260Hu61 Eukaryotic Beta-2-Microglobulin (b2M) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA260Hu01 Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
MAA260Hu22 Monoclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
LAA260Hu81 FITC-Linked Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IF.
LAA260Hu71 Biotin-Linked Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC.
PAA260Hu06 Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
Assay Kits SEA260Hu ELISA Kit for Beta-2-Microglobulin (b2M) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA260Hu CLIA Kit for Beta-2-Microglobulin (b2M) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA260Mu01 Recombinant Beta-2-Microglobulin (b2M) Positive Control; Immunogen; SDS-PAGE; WB.
RPA260Mu02 Recombinant Beta-2-Microglobulin (b2M) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA260Mu01 Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
LAA260Mu71 Biotin-Linked Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC.
LAA260Mu81 FITC-Linked Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IF.
PAA260Mu02 Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
MAA260Mu21 Monoclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
Assay Kits SEA260Mu ELISA Kit for Beta-2-Microglobulin (b2M) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA260Ra01 Recombinant Beta-2-Microglobulin (b2M) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA260Ra01 Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
LAA260Ra71 Biotin-Linked Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC.
LAA260Ra81 FITC-Linked Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IF.
MAA260Ra21 Monoclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
Assay Kits SEA260Ra ELISA Kit for Beta-2-Microglobulin (b2M) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Beta-2-Microglobulin (b2M) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Beta-2-Microglobulin (b2M) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Beta-2-Microglobulin (b2M) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Beta-2-Microglobulin (b2M) CLIA Kit Customized Service Offer
n/a ELISA Kit for Beta-2-Microglobulin (b2M) ELISA Kit Customized Service Offer

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA260Si01 Recombinant Beta-2-Microglobulin (b2M) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA260Si01 Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
Assay Kits SEA260Si ELISA Kit for Beta-2-Microglobulin (b2M) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA260Ca01 Recombinant Beta-2-Microglobulin (b2M) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA260Ca01 Polyclonal Antibody to Beta-2-Microglobulin (b2M) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Beta-2-Microglobulin (b2M) CLIA Kit Customized Service Offer
n/a ELISA Kit for Beta-2-Microglobulin (b2M) ELISA Kit Customized Service Offer
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