Interferon Alpha (IFNa)
[Edit]IFNA1; IFL; LeIF D; IFN; IFN-Alpha; IFNA13; IFN-A; IFNAP22; IFN-Alpha 1b; Interferon Alpha 1b; Interferon, Leukocytic; IFN, Leukocyte; Interferon alpha-D
-90033.jpg)
Streuli et al. (1980) showed that at least 3 different IFN-alpha genes are expressed in man. Furthermore, study of genomic DNA revealed the presence of at least 8 IFN genes.
Nagata et al. (1980) found that the alpha-interferon genes are devoid of intervening sequences. Using radioactive probes from purified cDNA clones of interferons, Owerbach et al. (1981) located at least 8 leukocyte interferon genes and a fibroblast interferon gene on chromosome 9. Shows et al. (1982) found that the alpha- and beta-interferon genes are on 9p. The mapping to 9pter-q12 was accomplished by blot hybridization of cloned interferon cDNA to DNA from human-mouse cell hybrids with a translocation involving chromosome 9.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Hu01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA033Hu61 | Eukaryotic Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA033Hu01 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| RPA033Hu02 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA033Hu01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| MAA033Hu22 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| PAA033Hu06 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| LAA033Hu71 | Biotin-Linked Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC. | |
| MAA033Hu26 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| PAA033Hu02 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Hu | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Hu | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Hu | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. | |
| AEA033Hu | ELISA Kit for Anti-Interferon Alpha Antibody (Anti-IFNa) | Enzyme-linked immunosorbent assay for Antibody Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Mu01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA033Mu61 | Eukaryotic Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA033Mu61 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| APA033Mu01 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| Antibodies | PAA033Mu01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| PAA033Mu06 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| LAA033Mu72 | Biotin-Linked Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC. | |
| LAA033Mu71 | Biotin-Linked Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC. | |
| LAA033Mu76 | Biotin-Linked Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC. | |
| PAA033Mu02 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| MAA033Mu21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| MAA033Mu22 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Mu | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Mu | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Mu | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Ra01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA033Ra61 | Eukaryotic Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA033Ra61 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| APA033Ra01 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| Antibodies | PAA033Ra01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| MAA033Ra21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| PAA033Ra06 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| MAA033Ra26 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Ra | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Ra | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Ra | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Cavia (Guinea pig )
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Gu01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA033Gu02 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA033Gu01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| MAA033Gu21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| PAA033Gu02 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Gu | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| IEA033Gu | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Rb01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA033Rb02 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA033Rb02 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| Antibodies | PAA033Rb51 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| LAA033Rb71 | Biotin-Linked Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC. | |
| MAA033Rb21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Rb | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Rb | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Rb | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rhesus monkey (Simian)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Si01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA033Si01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| MAA033Si21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Si | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Si | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Si | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Ca01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA033Ca02 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| EPA033Ca61 | Eukaryotic Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA033Ca01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| LAA033Ca81 | FITC-Linked Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IF. | |
| LAA033Ca71 | Biotin-Linked Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC. | |
| PAA033Ca02 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Ca | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Ca | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Ca | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Po01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA033Po61 | Eukaryotic Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA033Po61 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| APA033Po01 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| Antibodies | PAA033Po01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| LAA033Po81 | FITC-Linked Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IF. | |
| LAA033Po71 | Biotin-Linked Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC. | |
| MAA033Po21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| LAA033Po72 | Biotin-Linked Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC. | |
| Assay Kits | SEA033Po | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Po | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Po | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Bo01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA033Bo61 | Eukaryotic Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA033Bo01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| MAA033Bo21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Bo | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Bo | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Bo | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Ovis aries; Ovine (Sheep)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Ov01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA033Ov61 | Eukaryotic Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA033Ov61 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| Antibodies | MAA033Ov21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| PAA033Ov01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Ov | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Ov | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Ov | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Equus caballus; Equine (Horse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Eq01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA033Eq61 | Eukaryotic Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA033Eq01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| MAA033Eq21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Eq | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Eq | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Eq | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Chicken (Gallus)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA033Ga01 | Recombinant Interferon Alpha (IFNa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA033Ga01 | Active Interferon Alpha (IFNa) | Cell culture; Activity Assays. | |
| Antibodies | PAA033Ga01 | Polyclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. |
| MAA033Ga21 | Monoclonal Antibody to Interferon Alpha (IFNa) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA033Ga | ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA033Ga | CLIA Kit for Interferon Alpha (IFNa) | Chemiluminescent immunoassay for Antigen Detection. | |
| IEA033Ga | Instant ELISA Kit for Interferon Alpha (IFNa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "The nucleotide sequence of a cloned human leukocyte interferon cDNA."Gene 10:1-10(1980) [PubMed] [Europe PMC] [Abstract]
- "Human leukocyte and fibroblast interferons are structurally related."Nature 285:547-549(1980) [PubMed] [Europe PMC] [Abstract]
- "The structure of eight distinct cloned human leukocyte interferon cDNAs."Nature 290:20-26(1981) [PubMed] [Europe PMC] [Abstract]
- "Two non-allelic human interferon alpha genes with identical coding regions."EMBO J. 3:1809-1812(1984) [PubMed] [Europe PMC] [Abstract]
- "Structural relationship of human interferon alpha genes and pseudogenes."J. Mol. Biol. 185:227-260(1985) [PubMed] [Europe PMC] [Abstract]
- "Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides."Mol. Cell. Biol. 5:768-779(1985) [PubMed] [Europe PMC] [Abstract]
- "Novel cis-active structures in the coding region mediate CRM1-dependent nuclear export of IFN-alpha 1 mRNA."Med. Mol. Morphol. 43:145-157(2010) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli."Nucleic Acids Res. 11:5661-5669(1983) [PubMed] [Europe PMC] [Abstract]
- "Purification and characterization of multiple components of human lymphoblastoid interferon-alpha."J. Biol. Chem. 267:15210-15216(1992) [PubMed] [Europe PMC] [Abstract]
- "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes."Biochem. J. 329:295-302(1998) [PubMed] [Europe PMC] [Abstract]
- "IFN-alpha-1a gene is the major variant in the North American population."J. Interferon Cytokine Res. 20:763-768(2000) [PubMed] [Europe PMC] [Abstract]
- "Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus."J. Mol. Med. 90:837-846(2012) [PubMed] [Europe PMC] [Abstract]