Monoclonal Antibody to Interferon Alpha (IFNa)

IFNA1; IFL; LeIF D; IFN; IFN-Alpha; IFNA13; IFN-A; IFNAP22; IFN-Alpha 1b; Interferon Alpha 1b; Interferon, Leukocytic; IFN, Leukocyte; Interferon alpha-D

SPECIFITY

The antibody is a mouse monoclonal antibody raised against IFNa. It has been selected for its ability to recognize IFNa in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
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Journal of Animal and Veterinary Advances Immunostimulatory Effects of Arginine in Broiler Chickens Challenged with Vaccine Strain of Infectious Bursal Disease Virus Medwell: 2010594600
Ann Rheum Dis. The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats PubMed: 23172753
Nanomedicine Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform PubMed: 23394132
International journal of experimental pathology Experimental rat model for alcohol-induced osteonecrosis of the femoral head PubMed: PMC3781777
Antiviral Research A recombinant adenovirus bicistronically expressing porcine interferon-α and interferon-γ enhances antiviral effects against foot-and-mouth disease virus ScienceDirect: S0166354214000266
British Journal of Pharmacology Andrographolide exerts anti-hepatitis C virus activity by up-regulating haeme oxygenase-1 via the p38 MAPK/Nrf2 pathway in human hepatoma cells Onlinelibrary: bph.12440
BMC Cancer High efficiency of alphaviral gene transfer in combination with 5-fluorouracil in a mouse mammary tumor model Pubmed:24950740
PLoS One. Respiratory Mechanics and Plasma Levels of Tumor Necrosis Factor Alpha and Interleukin 6 Are Affected by Gas Humidification during Mechanical Ventilation in Dogs Pubmed:25036811
Veterinary Research Infection of equine monocyte-derived macrophages with an attenuated equine infectious anemia virus (EIAV) strain induces a strong resistance to the infection by a virulent EIAV strain Pubmed:25106750
Asian Pac J Trop Med Effect of SecinH3 on lung injury induced by sepsis of rats PubMed: 26706678
PLoS One siRNA Targeting the 2A pro Genomic Region Prevents Enterovirus 71 Replication In Vitro Pubmed:26886455
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Veterinary microbiology Impact of porcine reproductive and respiratory syndrome virus and porcine circovirus-2 infection on the potency of the classical swine fever vaccine (LOM strain). pubmed:27599928
International Journal of Clinical and Experimental Pathology Host miR-146a promotes replication of human cytomegalovirus by suppressing type I IFN response in MRC-5 cells files:ijcep0036479.pdf
Scandinavian Journal of Immunology Serum Proteomics Analysis in Rats of Immunosuppression Induced by Chronic Stress. pubmed:27384769
Saudi Journal of Gastroenterology Deoxyschizandrin suppresses dss-induced ulcerative colitis in mice. pubmed:27976641
Biochemical and Biophysical Research Communications MicroRNA-548j inhibits type I interferon production by targeting ZBTB11 in patients with chronic hepatitis B pubmed:28342861
Virology The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection pubmed:28988058
Antiviral Research Coinjection of a vaccine and anti-viral agents can provide fast-acting protection from foot-and-mouth disease pubmed:28454913
Molecular Therapy. Methods & Clinical Development Anti-high mobility group box 1 antibody ameliorates albuminuria in MRL/lprlupus-prone mice pubmed:28649578
Journal of Virology Fucoidan from Fucus vesiculosus suppresses hepatitis B virus replication by enhancing extracellular signal-regulated Kinase activation. pubmed:28915824
Clinical Immunology Toll-like receptor 9 ligands increase type I interferon induced B-cell activating factor expression in chronic rhinosinusitis with nasal polyposis Pubmed:30056130
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LUPUS Collagen triple helix repeat containing-1: a novel biomarker associated with disease activity in Systemic lupus erythematosus Pubmed: 30336754
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international immunopharmacology Adenovirus-mediated down-regulation of miR-21-5p alleviates experimental autoimmune uveoretinitis in mice Pubmed: 31228813
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Transboundary and Emerging Diseases Pathogenicity of porcine reproductive and respiratory syndrome virus (ORF5 RFLP 1–7–4 viruses) in China Pubmed: 32187856
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Int Immunopharmacol BNIP3 deletion ameliorated enterovirus 71 infection-induced hand, foot and mouth disease via inhibiting apoptosis, autophagy, and inflammation in mice Pubmed: 32717566
Molecular Medicine Reports Aquaporin‑4 deletion ameliorates enterovirus 71 infection in mice Pubmed: 32582978
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