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Polyclonal Antibody to Collagen Type I (COL1)
- Product No.PAA571Mu01
- Organism SpeciesMus musculus (Mouse) Same name, Different species.
- SourcePolyclonal antibody preparation
- HostRabbit
- Potencyn/a
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- LabelNone
- Immunogen n/a
- Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
- TraitsLiquid
- Concentration0.5mg/mL
- Organism Species Moren/a
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies. - DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
- FOB
US$ 97
US$ 227
US$ 324
US$ 810
US$ 3240
For more details, please contact local distributors!
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against COL1. It has been selected for its ability to recognize COL1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
| Magazine | Citations |
| Journal of hypertension | Urotensin II induces phenotypic differentiation, migration, and collagen synthesis of adventitial fibroblasts from rat aorta PubMed: 18475149 |
| Cardiovascular Research | Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway OxfordJournals: source |
| Acta Otolaryngol | Serial cytokine levels during wound healing in rabbit maxillary sinus mucosa PubMed: 19958244 |
| Experimental Biology and Medicine | Acidic pH conditions mimicking degenerative intervertebral discs impair the survival and biological behavior of human adipose-derived mesenchymal stem cells Rsmjournals: Source |
| Connect Tissue Res. | Role of moderate exercising on Achilles tendon collagen crimping patterns and proteoglycans Pubmed: 23758268 |
| Bulletin of Experimental Biology and Medicine | Modification of collagen formation by mesenchymal stem cells isolated from human adipose tissue in culture and after autotransplantation for abdominal hernia plasty Pubmed: 24319714 |
| Age( dordr). | In vitro tenocyte metabolism in aging and oestrogen deficiency Springer: Source |
| PLoS ONE | A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches Plosone: Source |
| European Archives of Oto-Rhino-Laryngology | Age effects on extracellular matrix production of vocal fold scar fibroblasts in rats Pubmed: 24077847 |
| Stem Cell Research Therapy | Protein synthesis and secretion in human mesenchymal cells derived from bone marrow, adipose tissue and Wharton's jelly Pubmed: 24739658 |
| Physiol. Res. | The unwounded skin remodeling in animal models of diabetes types 1 and 2. Pubmed: 24020818 |
| J Physiol Pharmacol. | Fibrogenic response of hepatic stellate cells in ovarectomised rats exposed to ketogenic diet Pubmed: 23568967 |
| 22 | Combined effect of strontium and zoledronate on hydroxyapatite structure and bone cell responses ScienceDirect: S0142961214003135 |
| Journal of Clinical and Experimental Hepatology | Protective Effects of Norursodeoxycholic Acid Versus Ursodeoxycholic Acid on Thioacetamide-induced Rat Liver Fibrosis ScienceDirect: S0973688314000073 |
| Human Molecular Genetics Online | Dystrophic mdx mice develop severe cardiac and respiratory dysfunction following genetic ablation of the anti-inflammatory cytokine IL-10 Pubmed:24659498 |
| PLoS One. | Mesenchymal stromal cell proliferation, gene expression and protein production in human platelet-rich plasma-supplemented media Pubmed:Pmc4130592 |
| Journal of Biomedical Materials Research Part A | Carboxymethyl cellulose—hydroxyapatite hybrid hydrogel as a composite material for bone tissue engineering applications Pubmed:23720392 |
| Experimental Biology adn Medicine | Endostar, a novel human recombinant endostatin, attenuates liver fibrosis in CCl4-induced mice Pubmed:24872431 |
| International Journal of Clinical & Experimental Pathology | Mast cell chymase in keloid induces profibrotic response via transforming growth factor-β1/Smad activation in keloid fibroblasts Pubmed:25120737 |
| FEBS Letters | Low-intensity pulsed ultrasound-induced ATP increases bone formation via the P2X7 receptor in osteoblast-like MC3T3-E1 cells Pubmed:25542352 |
| Cardiology | KLF15 is an essential negative regulatory factor for the cardiac remodeling response to pressure overload Pubmed:25633973 |
| PLOS ONE | Impact of the Uremic Milieu on the Osteogenic Potential of Mesenchymal Stem Cells Pubmed:25635832 |
| Journal of Colloid and Interface Science | Strontium and zoledronate hydroxyapatites graded composite coatings for bone prostheses Pubmed:25706198 |
| Macromolecular Bioscience | Multi‐Layered Scaffolds for Osteochondral Tissue Engineering: In Vitro Response of Co‐Cultured Human Mesenchymal Stem Cells PubMed: 26126665 |
| journal of hard Tissue Biology | Biological Evaluation of a Prototype Material made of Polyglycolic Acid and Hydroxyapatite Article: Jhtb |
| Mol Med Rep | NIM811 downregulates transforming growth factor PubMed: 26573209 |
| Front Pharmacol | Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats PubMed: 26483688 |
| Chemosphere | Effects of fluoride on the ultrastructure and expression of Type I collagen in rat hard tissue PubMed: 25655816 |
| J Surg Res | Tanshinone IIA ameliorates bleomycin-induced pulmonary fibrosis and inhibits transforming growth factor-beta-β–dependent epithelial to mesenchymal transition PubMed: 25911951 |
| Molecular and Cellular Biochemistry | SVVYGLR motif of the thrombin-cleaved N-terminal osteopontin fragment enhances the synthesis of collagen type III in myocardial fibrosis PubMed: 26112906 |
| Biointerphases | Incorporation of nanostructured hydroxyapatite and poly(N-isopropylacrylamide) in demineralized bone matrix enhances osteoblast and human mesenchymal stem cell activity PubMed: 26443012 |
| Gels | On the Mechanism of Drug Release from Polysaccharide Hydrogels Cross-Linked with Magnetite Nanoparticles by Applying Alternating Magnetic Fields: the Case of DOXO Delivery 2310-2861: 1 |
| Acta Biomater | Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: an in vitro osteoblast-osteoclast-endothelial cell co-culture study PubMed: 26689470 |
| Int J Clin Exp Med | Uighur medicine abnormal savda munzip (ASMq) suppresses expression of collagen and TGF-β1 with concomitant induce Smad7 in human hypertrophic scar … PubMed: 26309506 |
| International Journal of Molecular Sciences | Hybrid Macro-Porous Titanium Ornamented by Degradable 3D Gel/nHA Micro-Scaffolds for Bone Tissue Regeneration Pubmed:27092492 |
| 中国眼耳鼻喉科杂志 | 白细胞介素10 上调表达对家兔慢性细菌性鼻窦炎黏膜创伤修复的影响 article:11593 |
| Acta Biomaterialia | Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: An in vitro osteoblast–osteoclast–endothelial cell co-culture study Pubmed:26689470 |
| scientific reports | IL-17A mediates inflammatory and tissue remodelling events in early human tendinopathy Pubmed:27263531 |
| Cell Mol Immunol | Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica Pubmed:27157496 |
| Кардіологія | Інфаркт міокарда, ускладнений аневризмою лівого шлуночка: клінічні і структурно-функціональні особливості перебігу, діагностичні, терапевтичні та прогностичні аспекти bitstream:123456789 |
| Inflammation Research | Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy pubmed:27516211 |
| Indian Journal of Pharmaceutical Education and Research | Inhibition of hesperidin on epithelial to mesenchymal transition of non-small cell lung cancer cells induced by TGF-β1 sites:default |
| Heart & Vessels | Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR pubmed:28004175 |
| biochemical and biophysical research communications | Positive feedback loop of YB-1 interacting with Smad2 promotes liver fibrosis. pubmed:28153731 |
| Frontiers in Pharmacology | Induced pluripotent stem cells inhibit bleomycin-induced pulmonary fibrosis in mice through suppressing TGF-β1/Smad-mediated epithelial to mesenchymal … PMC5108931 |
| International Journal of Molecular Sciences | Plasma LncRNA-ATB, a Potential Biomarker for Diagnosis of Patients with Coal Workers'Pneumoconiosis: A Case-Control Study. pubmed:27556453 |
| BMC Cancer | Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent andmitochondrial pathways in mammalian hepatic stellate cells. pubmed:27461108 |
| J Cell Physiol. | An advanced tri-culture model to evaluate the dynamic interplay among osteoblasts, osteoclasts, and endothelial cells. pubmed:28240358 |
| Basic Clin Pharmacol Toxicol. | Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4+ T Helper 17 (Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling. pubmed:28032440 |
| Acta Biomater. | Antiresorptive and anti-angiogenetic octacalcium phosphate functionalized with bisphosphonates: An in vitro tri-culture study. pubmed:28238916 |
| The American Journal of Chinese Medicine | Saikosaponin a Induces Apoptosis through Mitochondria-Dependent Pathway in Hepatic Stellate Cells pubmed:28231747 |
| Biomedical and Environmental Sciences | Crystalline Silica Promotes Rat Fibrocyte Differentiation in Vitro, and Fibrocytes Participate in Silicosis in Vivo pubmed:29081339 |
| Basic & Clinical Pharmacology & Toxicology | Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4 + T Helper 17(Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling doi:10.1111 |
| Dental Materials Journal | Involvement of the calcium-sensing receptor in mineral trioxide aggregate-induced osteogenic gene expression in murine MC3T3-E1 cells. pubmed:28228629 |
| Biomedicine & pharmacotherapy | Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation. pubmed:28742995 |
| Journal of Applied Biomaterials & Functional Materials | Demineralized dentin and enamel matrices as suitable substrates for bone regeneration pubmed:28731486 |
| Acta Biomaterialia | Selective effect of hydroxyapatite nanoparticles on osteoporotic and healthy bone formation correlates with intracellular calcium homeostasis regulation pubmed:28698163 |
| Advanced Healthcare Materials | Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events. pubmed:29120858 |
| Macromolecular Bioscience | Strontium‐Substituted Hydroxyapatite‐Gelatin Biomimetic Scaffolds Modulate Bone Cell Response Pubmed:29877029 |
| International Journal of Molecular Medicine | Adenovirus‑mediated knockdown of activin A receptor type 2A attenuates immune‑induced hepatic fibrosis in mice and inhibits interleukin‑17‑induced … Pubmed:29620144 |
| PLoS One | Effect of hyperbaric oxygen therapy (HBO) on implant-associated osteitis in a femur fracture model in mice Pubmed:29377928 |
| Royal Society of Chemistry | In vitro and in vivo assessment of nanostructured porous biphasic calcium phosphate ceramics for promoting osteogenesis in an osteoporotic environment c8ra00768c |
| European Food Research and Technology | Evaluation of antifibrotic effects of coffee and cocoa extracts in rats with thioacetamide-induced fibrosis 10.1007:s00217-018-3119-z |
| Journal of Applied Biomaterials & Functional Materials | BMP-2 and type I collagen preservation in human deciduous teeth after demineralization Pubmed:30045659 |
| Theriogenology | Effect of transforming growth factor-β1 on α-smooth muscle actin and collagen expression in equine endometrial fibroblasts Pubmed: 30321755 |
| ACS Applied Materials & Interfaces | Fabrication and characterization of core-shell nanofibers using a next-generation airbrush for biomedical applications Pubmed: 30433758 |
| Chemico-Biological Interactions | Lead exposure inhibits osteoblastic differentiation and inactivates the canonical Wnt signal and recovery by icaritin in MC3T3-E1 subclone 14 cells Pubmed: 30731080 |
| Oxidative Medicine and Cellular Longevity | Effects of the (Pro) renin Receptor on Cardiac Remodeling and Function in a Rat Alcoholic Cardiomyopathy Model via the PRR-ERK1/2-NOX4 Pathway |
| Tropical Journal of Pharmaceutical Research | Methylbenzoxime as a therapeutic agent for glucocorticoid-induced osteoporosis in rats. |
| Scientific Reports | Low fibrosis biomarker levels predict cardiac resynchronization therapy response Pubmed: 30988339 |
| Experimental Lung Research | High amplitude stretching of ATII cells and fibroblasts results in profibrotic effects Pubmed: 31290711 |
| BMC Nephrology | Serum sclerostin levels are positively related to bone mineral density in peritoneal dialysis patients: a cross-sectional study Pubmed: 31315601 |
| Archives of Dermatological Research | Extracellular matrix deposition by adipose-derived stem cells and fibroblasts: a comparative study Pubmed: 31616972 |
| Drug Delivery and Translational Research | A multifunctional dexamethasone-delivery implant fabricated using atmospheric plasma and its effects on apoptosis, osteogenesis and inflammation Pubmed: 31898081 |
| ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | Pantoea agglomerans chronic exposure induces epithelial-mesenchymal transition in human lung epithelial cells and mice lungs Pubmed: 32146192 |
| Molecular Metabolism | SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α Pubmed: 32029232 |
| ACS Applied Materials & Interfaces | ZIF-8 Modified Multifunctional Bone-Adhesive Hydrogels Promoting Angiogenesis and Osteogenesis for Bone Regeneration Pubmed: 32814397 |
| in vitro cellular & developmental biology-animal | Distinct differences in hypoxic responses between human oral mucosa and skin fibroblasts in a 3D collagen matrix Pubmed: 32588253 |
| Molecular Medicine | Circulating fibrocytes traffic to the lung in murine acute lung injury and predict outcomes in human acute respiratory distress syndrome: a pilot study Pubmed: 32460694 |
| Predictors of myocardial fibrosis and loss of epicardial adipose tissue volume in the long-term period after myocardial infarction | |
| ACS Biomaterials Science & Engineering | Tissue-Engineered Decellularized Allografts for Anterior Cruciate Ligament Reconstruction |
| Ассоциации толщины эпикардиального жира и циркулирующих маркеров фиброза миокарда у пациентов с инфарктом миокарда | |
| Ann Med Surg | Trauma magnitude of the meta-epyphyseal cancellous affects the incidence of deep vein thrombosis. A prospective cohort study on the dynamic of collagen I ¡ 33717478 |
| INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE | Uncarboxylated osteocalcin reverses the high glucose?induced inhibition of the osteogenic differentiation of MC3T3E1 cells via the GPRC6A/cAMP/PKA/AMPK signaling pathway 33786607 |
| PLoS One | Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment¡ªIn vivo studies 33999928 |
| Structural Changes and Detection of Liver Fibrosis¨CRelated Protein Levels in Coculture of Alveolar Echinococcosis-Protoscoleces and Human Hepatic Stellate cells | |
| Russian Journal of Cardiology | Early diagnosis of myocardial fibrosis in patients with epicardial obesity |
| Manuscript title Microparticles Containing MiR-625-5p In Coronary Artery Reduce Myocardial Fibrosis After Myocardial Infarction | |
| Parasit Vectors | Structural changes and expression of hepatic fibrosis-related proteins in coculture of Echinococcus multilocularis protoscoleces and human hepatic stellate … 34857049 |
| Pharmacol Res | Esomeprazole Alleviates Fibrosis in Systemic Sclerosis by Modulating AhR/Smad2/3 Signaling Pubmed:34995795 |
| Catalog No. | Related products for research use of Mus musculus (Mouse) Organism species | Applications (RESEARCH USE ONLY!) |
| PAA571Mu01 | Polyclonal Antibody to Collagen Type I (COL1) | WB; IHC; ICC; IP. |
| SEA571Mu | ELISA Kit for Collagen Type I (COL1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA571Mu | Multiplex Assay Kit for Collagen Type I (COL1) ,etc. by FLIA (Flow Luminescence Immunoassay) | FLIA Kit for Antigen Detection. |