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Monoclonal Antibody to Corticosterone (Cort)

Corticosrone

SPECIFITY

The antibody is a mouse monoclonal antibody raised against Cort. It has been selected for its ability to recognize Cort in immunohistochemical staining and western blotting.

USAGE

Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Respir Res. Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats. PubMed: 20403205
Natural Product Sciences Effects of Gypenosides on Acute Stress in Mice Papersearch: Source
Neuropeptides.? Role of adrenomedullin in the cerebrospinal fluid-contacting nucleus in the modulation of immobilization stress Pubmed:25911494
EXPERIMENTAL & CLINICAL CARDIOLOGY Sick Sinus Syndrome May Attribute to the Decrease of ?±-klotho Protein in Mice Com:Source
Journal of Pharmacological Sciences Organ-Specific Activation of the Gastric Branch of the Efferent Vagus Nerve by Ghrelin in Urethane-Anesthetized Rats Pubmed:24366191
Toxicology Letters Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic–pituitary–adrenal axis in adult male rats Pubmed:24440345
Stress. Restraint stress alters immune parameters and induces oxidative stress in the mouse uterus during embryo implantation Pubmed:25238024
Int J Clin Exp Med Diabetes alters the blood glucose response to ketamine in streptozotocin-diabetic rats PubMed: 26379948
Pakistan Veterinary Journal Trivalent Chromium Attenuated Corticosterone Secretion and Actions in Adrenocorticotropic Hormone-Stimulated Rats In_Press: 15-058.Pdf
BMC Ameliorating effects of gypenosides on chronic stress-induced anxiety disorders in mice PubMed: 26370834
Behav Brain Res Rats with differential self-grooming expression in the elevated plus-maze do not differ in anxiety-related behaviors PubMed: 26142783
Archives of Physiology and Biochemistry Improvement of oral contraceptive-induced glucose dysreCavia (Guinea pig )lation and dyslipidemia by valproic acid is independent of circulating corticosterone Pubmed:26855320
Archives of Physiology and Biochemistry Activation of cardiac renin–angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder Pubmed:26934364
Neuroscience Letters Electroacupuncture reCavia (Guinea pig )late hypothalamic–pituitary–adrenal axis and enhance hippocampal serotonin system in a rat model of depression Pubmed:26773866
Neural Regeneration Research Moxibustion upreCavia (Guinea pig )lates hippocampal progranulin expression. Pubmed:27212922
Environmental Science and Pollution Research Lycopene ameliorates atrazine-induced oxidative damage in adrenal cortex of male rats by activation of the Nrf2/HO-1 pathway Pubmed:27102619
Eur Neuropsychopharmacol Apelin-13 exerts antidepressant-like and recognition memory improving activities in stressed rats Pubmed:26853763
experimental brain research Dopamine D2-like receptors modulate freezing response, but not the activation of HPA axis, during the expression of conditioned fear. pubmed:27766352
brain research bulletin Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus. pubmed:28161195
Neurochemical Research  Effects of (-)-Sesamin on Chronic Stress-Induced Anxiety Disorders in Mice pubmed:27995494
Journal of Molecular Histology Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea pubmed:29260435
Psychosomatic Medicine The Role of Psychological Stress on Heart Autophagy in Mice With Heart Failure pubmed:28691995
Scientific Reports COMMUNICATIONS Environmental perturbation of the circadian clock during pregnancy leads to transgenerational mood disorder-like behaviors in mice pubmed:28974783
BMC Gastroenterology Role of serotonin on the intestinal mucosal immune response to stress-induced diarrhea in weaning mice pubmed:28633646
biorxiv Anxiety-like but not despair-like behaviors are further aggravated by chronic mild stress in the early stages of APPswe/PS1dE9 transgenic mice doi.org/10.1101/202283
Frontiers in Molecular Neuroscience Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. pubmed:28959186
Biochemical Pharmacology Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats Pubmed:30028991
Toxicological Sciences Impact of Perfluorooctane Sulfonate on Reproductive Ability of Female Mice through Suppression of Estrogen Receptor a-Activated Kisspeptin Neurons 10.1093:toxsci
Nutrition Multigenerational effects of dietary macronutrients intake on the metabolic phenotype of male Wistar rats 10.1016:j.nut.2018.06.008
Behavioural Brain Research Depressive-and anxiety-like phenotypes in young adult APPSwe/PS1dE9 transgenic mice with insensitivity to chronic mild stress Pubmed:30012417
Stress Blockade of AT1 type receptors for angiotensin II prevents cardiac microvascular fibrosis induced by chronic stress in Sprague–Dawley rats Pubmed:29676198
Inflammation Differential Effects of Brain Death on Rat Microcirculation and Intestinal Inflammation: Female Male Pubmed:29737476
Respiratory physiology & neurobiology Curcumin attenuates chronic intermittent hypoxia-induced brain injuries by inhibiting AQP4 and p38 MAPK pathway Pubmed:29758366
Nature and Science of Sleep Chronic treatment with dexamethasone alters clock gene expression and melatonin synthesis in rat pineal gland at night Pubmed:30046256
Journal of Pharmacy and Pharmacology Tannins from fruits attenuates GABA antagonist‐induced anxiety‐like behaviour modulation of neurotransmitters Pubmed: 30198561
Bulletin of Experimental Biology and Medicine Expression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia. Corticosterone in … Pubmed: 30353332
Brain, Behavior, and Immunity HMGB1-Mediated Differential Response on Hippocampal Neurotransmitter Disorder and Neuroinflammation in Adolescent Male and Female Mice following Cold Exposure Pubmed: 30476565
Heliyon Establishment and evaluation of a novel mouse model of peri/postmenopausal depression Doi: 10.1016/j.heliyon.2019.e01195
Scientific Reports Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive-and anxiety-like behaviour, and gut microbiome composition Pubmed: 31015500
Food & Function Antidepressant-like effects of dietary gardenia blue pigment derived from genipin and tyrosine Doi: 10.1039/C9FO00480G
Neuroscience Letters Synaptic structure and alterations in the hippocampus in neonatal rats exposed to lipopolysaccharide Pubmed: 31288048
FASEB Journal Contribution of DNA methylation in chronic stress–induced cardiac remodeling and arrhythmias in mice Pubmed: 31431066
Cells MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model Pubmed: 31540304
endocrine journal Mice with nucleus tractus solitarius injury induced by chronic restraint stress present impaired ability to raise blood glucose and glucagon levels when blood glucose … Pubmed: 32249244
INTERNATIONAL IMMUNOPHARMACOLOGY GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and … Pubmed: 33166810
neurochemical research Anxiolytic and Anti‑depressive Like Effects of Translocator Protein (18 kDa) Ligand YL‑IPA08 in a Rat Model of Postpartum Depression Pubmed: 32383026
BioMed Research International Pathophysiological Changes in Female Rats with Estrous Cycle Disorder Induced by Long-Term Heat Stress Pubmed: 32685488
博士论文 Neurobiological determinants of depressive-like symptoms in rodents
Behavioral Ecology and Sociobiology  Exposure to eagle owl feces induces anti-predator behavior, physiology, and hypothalamic gene responses in a subterranean rodent, the plateau zokor (Eospalax …
Ther Adv Chronic Dis Empagliflozin improves chronic hypercortisolism-induced abnormal myocardial structure and cardiac function in mice 33294147
International Journal of?Nanomedicine Water-Soluble Carbon Dots in Cigarette Mainstream Smoke: Their Properties and the Behavioural, Neuroendocrinological, and Neurotransmitter Changes They ¡­ 33762821
CRYOBIOLOGY O-GlcNAc/Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress 33651993
NEUROSCIENCE RESEARCH Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats 33785408
Biomed Res Int A Famous Chinese Medicine Formula: Yinhuo Decoction Antagonizes the Damage of Corticosterone to PC12 Cells and Improves Depression by Regulating … Pubmed:35281603
Ecotoxicol Environ Saf Monochromatic blue light not green light exposure is associated with continuous light-induced hepatic steatosis in high fat diet fed-mice via oxidative stress Pubmed:35588616
Catalog No. Related products for research use of Pan-species (General) Organism species Applications (RESEARCH USE ONLY!)
CPA540Ge11 BSA Conjugated Corticosterone (Cort) Immunogen; SDS-PAGE; WB.
CPA540Ge21 OVA Conjugated Corticosterone (Cort) Immunogen; SDS-PAGE; WB.
CPA540Ge31 KLH Conjugated Corticosterone (Cort) Immunogen; SDS-PAGE; WB.
PAA540Ge01 Polyclonal Antibody to Corticosterone (Cort) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
PAA540Ge02 Polyclonal Antibody to Corticosterone (Cort) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
LAA540Ge71 Biotin-Linked Polyclonal Antibody to Corticosterone (Cort) WB; IHC; ICC.
LAA540Ge81 FITC-Linked Polyclonal Antibody to Corticosterone (Cort) WB; IHC; ICC; IF.
MAA540Ge28 Monoclonal Antibody to Corticosterone (Cort) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
MAA540Ge21 Monoclonal Antibody to Corticosterone (Cort) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
MAA540Ge22 Monoclonal Antibody to Corticosterone (Cort) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
LAA540Ge72 Biotin-Linked Monoclonal Antibody to Corticosterone (Cort) WB; IHC; ICC.
CEA540Ge ELISA Kit for Corticosterone (Cort) Enzyme-linked immunosorbent assay for Antigen Detection.
WEA540Ge Wide-range ELISA Kit for Corticosterone (Cort) Enzyme-linked immunosorbent assay for Antigen Detection.
MEA540Ge Mini Samples ELISA Kit for Corticosterone (Cort) Enzyme-linked immunosorbent assay for Antigen Detection.
CCA540Ge CLIA Kit for Corticosterone (Cort) Chemiluminescent immunoassay for Antigen Detection.
LMA540Ge Multiplex Assay Kit for Corticosterone (Cort) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSA540Ge11 ELISA Kit DIY Materials for Corticosterone (Cort) Main materials for "Do It (ELISA Kit) Yourself".