Aesculetin (Aes)

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Esculetin; 6,7-dihydroxycoumarin; Cichorigenin

Aesculetin (Aes)
Aesculetin is a derivative of coumarin. It is a natural lactone that derives from the intramolecular cyclization of a cinnamic acid derivative. It is present in chicory and in many toxic and medicinal plants, in form of glycosides and caffeic acid conjugates. Esculetin-containing preparations used systemically can have an anticoagulant effect and might interact with anticoagulent drugs such as warfarin. This compound is used in some sunscreens, but there is evidence that it acts as a photosensitizer for DNA damage. The sodium salt of its methyl-derivative is used in dermatology for the treatment of varicose veins. It is a blue fluorescence compound found in plants. Aesculin, the glucoside of aesculetin, will fluoresce under long wave ultraviolet light (360 nm). The hydrolysis of aesculin results in loss of this fluorescence. Aesculetin has the ability to quench the inner fluorescence of bovine serum albumin.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Aesculetin (Aes) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aesculetin (Aes) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aesculetin (Aes) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aesculetin (Aes) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aesculetin (Aes) ELISA Kit Customized Service Offer