![Ononin (Ono)](/upload/item/img/Ononin-(Ono)-V461.gif)
Ononin is one of several known isoflavones. Ononin is found in a number of plants and herbs like soybean and from Glycyrrhiza uralensis. Ononin is the 7-O-glucoside of formononetin.
A sensitive and reliable ultra-pressure liquid chromatography with tandem mass spectrometry (UPLC-MS) was developed and validated for simultaneous quantification of six main bioactive components, i.e., calycosin-7-O-β-D-glucoside, ononin, calycosin, formononetin, astragaloside IV, and astragaloside II in rat plasma after oral administration of the 95 % ethanol extraction from Radix Astragali. The proposed method was for the first time to compare the pharmacokinetic difference between calycosin-7-O-β-D-glucoside and calycosin in rat plasma, so as between ononin and formononetin, and studied to the astragaloside II pharmacokinetics in rat plasma.
A sensitive and reliable ultra-pressure liquid chromatography with tandem mass spectrometry (UPLC-MS) was developed and validated for simultaneous quantification of six main bioactive components, i.e., calycosin-7-O-β-D-glucoside, ononin, calycosin, formononetin, astragaloside IV, and astragaloside II in rat plasma after oral administration of the 95 % ethanol extraction from Radix Astragali. The proposed method was for the first time to compare the pharmacokinetic difference between calycosin-7-O-β-D-glucoside and calycosin in rat plasma, so as between ononin and formononetin, and studied to the astragaloside II pharmacokinetics in rat plasma.
Organism species: Pan-species (General)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Complete Antigen of Ononin (Ono) | Antigenic Transformation Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ononin (Ono) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ononin (Ono) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ononin (Ono) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ononin (Ono) | ELISA Kit Customized Service Offer |