Solasonineis a glycoside of solasodine. Solasonine occurs in plants of the Solanaceae family. Solasonine was one component of the unsuccessful experimental cancer drug candidate Coramsine.Solanum lycocarpum is native to the Brazilian Cerrado. Fruits of this species contain the glycoalkaloids solasonine (SN) and solamargine (SM), which display antiparasitic and anticancer properties. A method has been developed for the extraction and HPLC-UV analysis of the SN and SM in different parts of S. lycocarpum, mainly comprising ripe and unripe fruits, leaf, and stem. Certain glycoalkaloids, such as solasonine (SN) and solamargine (SM), stand out economically because their chemical structures are very similar to steroidal hormones and therefore have been proposed to be used as an important source for the production of medicines, such as contraceptives and steroidal anti-inflammatory drugs.
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