Retinol Binding Protein 5, Cellular (RBP5)
[Edit]CRBPIII; HRBPiso; Cellular retinol-binding protein III
![Retinol Binding Protein 5, Cellular (RBP5)](/upload/item/img/Retinol-Binding-Protein-5--Cellular-(RBP5)-83169.jpg)
The deduced 135-amino acid protein has a calculated molecular mass of 15.9 kD and shares 55.6% and 49.6% amino acid identity with RBP1 and RBP2, respectively. RNA dot-blot analysis of human tissues detected strong expression of RBP5 in adult kidney and liver with weak expression in fetal spleen, adult spleen, lymph node, appendix, fetal liver, and fetal kidney. Comparison of hybridization signals showed that RBP5 transcript levels in kidney and liver exceeded those of RBP1 by approximately 200 and 13 times, respectively.
RBP5 bound all-trans retinol, and they suggested that RBP5 binds the retinol ligand with a specific interaction similar to that observed in the retinol-RBP1 complex. They estimated a binding of 0.66 mol of retinol ligand per mol of RBP5 and apparent Kd of 60 nM.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPP169Hu01 | Recombinant Retinol Binding Protein 5, Cellular (RBP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPP169Hu02 | Recombinant Retinol Binding Protein 5, Cellular (RBP5) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAP169Hu01 | Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IP. |
PAP169Hu02 | Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IP. | |
Assay Kits | SEP169Hu | ELISA Kit for Retinol Binding Protein 5, Cellular (RBP5) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPP169Ra01 | Recombinant Retinol Binding Protein 5, Cellular (RBP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAP169Ra01 | Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IP. |
LAP169Ra71 | Biotin-Linked Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC. | |
MAP169Ra21 | Monoclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IP. | |
Assay Kits | n/a | CLIA Kit for Retinol Binding Protein 5, Cellular (RBP5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Retinol Binding Protein 5, Cellular (RBP5) | ELISA Kit Customized Service Offer |
Organism species: Oryctolagus cuniculus (Rabbit)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPP169Rb01 | Recombinant Retinol Binding Protein 5, Cellular (RBP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAP169Rb51 | Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IP. |
LAP169Rb71 | Biotin-Linked Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC. | |
LAP169Rb81 | FITC-Linked Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IF. | |
PAP169Rb01 | Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IP. | |
Assay Kits | SEP169Rb | ELISA Kit for Retinol Binding Protein 5, Cellular (RBP5) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPP169Bo01 | Recombinant Retinol Binding Protein 5, Cellular (RBP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAP169Bo01 | Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC |
LAP169Bo71 | Biotin-Linked Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC. | |
LAP169Bo81 | FITC-Linked Polyclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IF. | |
MAP169Bo21 | Monoclonal Antibody to Retinol Binding Protein 5, Cellular (RBP5) | WB; IHC; ICC; IP. | |
Assay Kits | n/a | CLIA Kit for Retinol Binding Protein 5, Cellular (RBP5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Retinol Binding Protein 5, Cellular (RBP5) | ELISA Kit Customized Service Offer |
- "Identification, retinoid binding and X-ray analysis of a human retinol-binding protein."Proc. Natl. Acad. Sci. U.S.A. 98:3710-3715(2001) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Down-regulation of retinol binding protein 5 is associated with aggressive tumor features in hepatocellular carcinoma."J. Cancer Res. Clin. Oncol. 133:929-936(2007) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]