Myricanone (Myr)
Myricanone is a cyclic diarylheptanoid isolated from the bark of Myrica rubra (Myricaceae). Ten cyclic diarylheptanoids (1-10), including three new compounds: myricanone 5-O-alpha-L-arabinofuranosyl-(1-->6)-beta-D-glucopyranoside (7), myricanone 17-O-beta-D-(6'-O-galloyl)-glucopyranoside (8), and 16-methoxy acerogenin B 9-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (10), along with two flavonoids (11, 12), were isolated from the extracts of Myrica rubra (Myricaceae) bark. The structures of new compounds were determined on the basis of spectroscopic methods. On evaluation of compounds 1-12 against the melanogenesis in the B16 melanoma cells, six compounds, 3, 5, 7, 8, 10, and 12, exhibited inhibitory effects with 30-56% reduction of melanin content at 25 microg/mL with no or very weak toxicity to the cells (82-103% of cell viability at 25 microg/mL).

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Myricanone (Myr) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myricanone (Myr) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myricanone (Myr) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myricanone (Myr) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myricanone (Myr) ELISA Kit Customized Service Offer