Cynaroside (Cyn)

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Glucoluteolin; Luteoloside; Cinaroside; 7-Glucoluteolin; 7-Glucosylluteolin; Luteolin 7-glucoside

Cynaroside (Cyn)
Cynaroside is a flavonoid compound that exhibits anti-oxidative capabilities. However, little is known about its effect on oxidative injury to cardiac myocytes and the underlying mechanisms. This study was designed to investigate the protective effects of cynaroside against H(2) O(2) -induced apoptosis in H9c2 cardiomyoblasts. H9c2 cells were pretreated with cynaroside for 4 h before exposure to 150 µM H(2) O(2) for 6  h. H(2) O(2) treatment caused severe injury to the H9c2 cells, which was accompanied by apoptosis, as revealed by analysis of cell nuclear morphology, through Annexin V FITC/PI staining and caspase proteases activation. Cynaroside pretreatment significantly reduced the apoptotic rate by enhancing the endogenous anti-oxidative activity of superoxide dismutase, glutathione peroxidase, and catalase, thereby inhibiting intracellular reactive oxygen species (ROS) generation.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Cynaroside (Cyn) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cynaroside (Cyn) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cynaroside (Cyn) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cynaroside (Cyn) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cynaroside (Cyn) ELISA Kit Customized Service Offer