Desmethoxycurcumin (DMC)

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Curcumin II; Desmethoxycurcumin; Monodemethoxycurcumin

Desmethoxycurcumin (DMC)
Desmethoxycurcumin is a curcuminoid found in turmeric.Commercial grade curcumin is widely used as a yellow coloring agent and spice in foods. In the present study topical application of commercial grade curcumin, pure curcumin or demethoxycurcumin had an equally potent inhibitory effect on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced increases in ornithine decarboxylase activity and TPA-induced tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated mouse skin. Bisdemethoxycurcumin and tetrahydrocurcumin were less active. In additional studies we found that commercial grade curcumin, pure curcumin, demethoxycurcumin and bisdemethoxycurcumin had about the same potent inhibitory effect on TPA-induced inflammation of mouse ears, as well as TPA-induced transformation of cultured JB6 (P+) cells. Tetrahydrocurcumin was less active.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Desmethoxycurcumin (DMC) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Desmethoxycurcumin (DMC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Desmethoxycurcumin (DMC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Desmethoxycurcumin (DMC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Desmethoxycurcumin (DMC) ELISA Kit Customized Service Offer