Methacholine (MC)
Methacholine is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system. Methacholine is primarily used to diagnose bronchial hyperreactivity, which is the hallmark of asthma and also occurs in chronic obstructive pulmonary disease. This is accomplished through the bronchial challenge test, or methacholine challenge, in which a subject inhales aerosolized methacholine, leading to bronchoconstriction. Other therapeutic uses are limited by its adverse cardiovascular effects, such as bradycardia and hypotension, which arise from its function as a cholinomimetic. It is highly active at all of the muscarinic receptors, but has little effect on the nicotinic receptors. Methacholine has a charged quaternary amine structure, rendering it insoluble to lipid cell membranes.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Methacholine (MC) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Methacholine (MC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Methacholine (MC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Methacholine (MC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Methacholine (MC) ELISA Kit Customized Service Offer