Ustekinumab (UKN)

[Edit]

CNTO 1275; Stelara; Centocor

Ustekinumab (UKN)
Ustekinumab is a human monoclonal antibody. It is directed against interleukin 12 and interleukin 23, naturally occurring proteins that regulate the immune system and immune-mediated inflammatory disorders. A third Phase III trial, ACCEPT, compared the efficacy and safety of ustekinumab with etanercept in the treatment of moderate to severe plaque psoriasis. This trial found a significantly higher clinical response with ustekinumab over the 12-week study period compared to high-dose etanercept. It also demonstrated the clinical benefit of ustekinumab among patients who failed to respond to etanercept. CNTO 1275 is designed to interfere with the triggering of the body's inflammatory response through the suppression of certain cytokines. Specifically, CNTO 1275 blocks interleukin IL-12 and IL-23 which help activate certain T-cells.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Ustekinumab (UKN) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ustekinumab (UKN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ustekinumab (UKN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ustekinumab (UKN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ustekinumab (UKN) ELISA Kit Customized Service Offer