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Angiopoietin Like Protein 5 (ANGPTL5)

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Angiopoietin-related protein 5

Angiopoietin Like Protein 5 (ANGPTL5)
CCC N613
HGNC 19705
PubMed 19075393
UniProt Q86XS5
The angiopoietins are a family of growth factors specific for vascular endothelium. During large-scale DNA sequencing of a human fetal brain cDNA library, Zeng et al. (2003) cloned a novel human angiopoietin-like cDNA and termed it angiopoietin-like-5 (ANGPTL5). Like other members of the angiopoietin family, the deduced 388-amino acid ANGPTL5 protein has an N-terminal cleavable signal peptide, a predicted coiled-coil domain, and a fibrinogen-like domain. RT-PCR analysis detected expression of ANGPTL5 in all tissues tested, but mainly in adult human heart.
Zeng et al. (2003) determined that the ANGPTL5 gene contains 8 exons and spans approximately 17.3 kb.By genomic sequence analysis, Zeng et al. (2003) mapped the ANGPTL5 gene to chromosome 11q22.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPN613Hu01 Recombinant Angiopoietin Like Protein 5 (ANGPTL5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAN613Hu01 Polyclonal Antibody to Angiopoietin Like Protein 5 (ANGPTL5) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Angiopoietin Like Protein 5 (ANGPTL5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Angiopoietin Like Protein 5 (ANGPTL5) ELISA Kit Customized Service Offer
  1. "Identification of a novel human angiopoietin-like gene expressed mainly in heart."J. Hum. Genet. 48:159-162(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]