Vincamine (VCN)

Vincamine is a peripheral vasodilator that increases blood flow to the brain. Generic drugs containing vincamine exist in specific regions. Most common drug preparations are in the sustained release forms. Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor, comprising about 25-65% of the indole alkaloids found in Vinca minor by weight. It can be synthesized from related alkaloids. Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics for a variety of purposes. The therapeutic efficacy of vincamine was clearly demonstrated by confirmatory analysis as the drug was statistically significantly superior to placebo in all four target variables.it can be accepted that the therapeutic effect of vincamine is superior to placebo in patients with mild to moderate dementia of degenerative and vascular etiologies.