GLIS Family Zinc Finger Protein 1 (GLIS1)

[Edit]

GLI-similar 1

GLIS Family Zinc Finger Protein 1 (GLIS1)
GLIS1 is a GLI-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription. The deduced 789-amino acid protein contains a bipartite nuclear localization signal, a proline-rich region, and a zinc finger domain consisting of 5 tandem C2H2-type zinc finger motifs. Northern blot analysis of mouse tissues detected highest expression of Glis1 in placenta and kidney, lower expression in testis, and little expression in other tissues examined. RT-PCR analysis detected high expression in kidney, low expression in brain, colon, brown fat, testis, and thymus, and no expression in lung, spleen, liver, pancreas, and muscle, In situ hybridization of mouse embryos showed that Glis1 was expressed primarily in the mesodermal lineages, including craniofacial regions, branchial arches, somites, vibrissal and hair follicles, limb buds, and myotomes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM536Hu01 Recombinant GLIS Family Zinc Finger Protein 1 (GLIS1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to GLIS Family Zinc Finger Protein 1 (GLIS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to GLIS Family Zinc Finger Protein 1 (GLIS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for GLIS Family Zinc Finger Protein 1 (GLIS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for GLIS Family Zinc Finger Protein 1 (GLIS1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] and Testis.
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]