Epirubicin (ERB)
Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death. Binding to cell membranes and plasma proteins may be involved in the compound's cytotoxic effects. Epirubicin also generates free radicals that cause cell and DNA damage. Epirubicin is favoured over doxorubicin, the most popular anthracycline, in some chemotherapy regimens as it appears to cause fewer side-effects. Epirubicin is primarily used against breast and ovarian cancer, gastric cancer, lung cancer and lymphomas.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Epirubicin (ERB) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epirubicin (ERB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epirubicin (ERB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epirubicin (ERB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epirubicin (ERB) ELISA Kit Customized Service Offer