Nilotinib (NLT)
Nilotinib in the form of the hydrochloride monohydrate salt, is a small molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia. Phase I clinical trial found nilotinib has a relatively favorable safety profile and shows activity in cases of CML resistant to treatment with imatinib, another tyrosine kinase inhibitor currently used as a first-line treatment. In that study 92% of patients achieved a normal white blood cell counts after five months of treatment. The use of low doses of nilotinib is being investigated for use for Parkinson's and Alzheimer's disease, as well as for ALS, dementia and Huntington's disease. Hypersensitivity to nilotinib or any of its excipients, long QT syndrome, hypokalaemia, hypomagnesaemia, pregnancy, planned pregnancy, lactation and galactose/lactose intolerance are the only contraindications.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Nilotinib (NLT) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nilotinib (NLT) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nilotinib (NLT) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nilotinib (NLT) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nilotinib (NLT) ELISA Kit Customized Service Offer