Azathioprine (AZA)
Azathioprine is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues. Synthesized originally as a cancer drug and a prodrug for mercaptopurine in 1957, it has been widely used as an immunosuppressant for more than 50 years. Azathioprine acts as a prodrug for mercaptopurine, inhibiting an enzyme that is required for the synthesis of DNA. Thus it most strongly affects proliferating cells, such as the T cells and B cells of the immune system. The main adverse effect of azathioprine is bone marrow suppression, which can be life-threatening, especially in people with a genetic deficiency of the enzyme thiopurine S-methyltransferase. It is also listed by the International Agency for Research on Cancer as a Group 1 carcinogen (carcinogenic to humans).

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Azathioprine (AZA) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Azathioprine (AZA) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Azathioprine (AZA) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Azathioprine (AZA) CLIA Kit Customized Service Offer
n/a ELISA Kit for Azathioprine (AZA) ELISA Kit Customized Service Offer