Levosalbutamol (Lev)

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Levalbuterol; Xopenex

Levosalbutamol (Lev)
Levosalbutamol is the R-enantiomer of the short-acting β2-adrenergic receptor agonist salbutamol. Activation of beta2-adrenergic receptors on airway smooth muscle leads to the activation of adenylate cyclase and to an increase in the intracellular concentration of cyclic-3', 5' -adenosine monophosphate (cyclic AMP). The increase in cyclic AMP is associated with the activation of protein kinase A, which in turn, inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in muscle relaxation.Levosalbutamol relaxes the smooth muscles of all airways, from the trachea to the terminal bronchioles. Increased cyclic AMP concentrations are also associated with the inhibition of the release of mediators from mast cells in the airways. Levosalbutamol acts as a functional agonist that relaxes the airway irrespective of the spasmogen involved, thereby protecting against all bronchoconstrictor challenges.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Levosalbutamol (Lev) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Levosalbutamol (Lev) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Levosalbutamol (Lev) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Levosalbutamol (Lev) CLIA Kit Customized Service Offer
n/a ELISA Kit for Levosalbutamol (Lev) ELISA Kit Customized Service Offer