Diltiazem (DTZ)
Diltiazem is a nondihydropyridine (non-DHP) member of the class of drugs known as calcium channel blockers, used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It is a benzothiazepine, which differentiates it from the other classes of non-DHP calcium channel blockers such as the phenylalkylamines. It is also an effective preventive medication for migraine. It is a class 3 antianginal drug, and a class IV antiarrhythmic.It incites minimal reflex sympathetic changes. It is based upon a 1,4-thiazepine ring. Diltiazem is metabolized by and acts as an inhibitor of the CYP3A4 enzyme. Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil. It is a potent vasodilator of coronary and peripheral vessels, which reduces peripheral resistance and afterload.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Diltiazem (DTZ) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Diltiazem (DTZ) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Diltiazem (DTZ) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Diltiazem (DTZ) CLIA Kit Customized Service Offer
n/a ELISA Kit for Diltiazem (DTZ) ELISA Kit Customized Service Offer