Benzisothiazolinone (BIT)

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Benzisothiazolin-3-One; Benzisothiazolone

Benzisothiazolinone (BIT)
Benzisothiazolinone (BIT) is a widely used biocide and belongs to the group of isothiazolinones. Benzisothiazolinone has a microbicide and a fungicide mode of action. It is used as a preservative in emulsion paints, varnishes, adhesives, washing agents, fuels and in the papermaking process. In paints, it is commonly used as a mixture with methylisothiazolinone. Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone. The regulation of 2-arachidonoylglycerol (2-AG) levels is a major issue as 2-AG has been proven to participate in numerous physiopathological phenomena such as neuroprotection or analgesia. Octhilinone, a cysteine-reagent compound, has recently been shown to inhibit in the nanomolar range monoacylglycerol lipase (MAGL), the major enzyme responsible for the degradation of 2-AG.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Benzisothiazolinone (BIT) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Benzisothiazolinone (BIT) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Benzisothiazolinone (BIT) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Benzisothiazolinone (BIT) CLIA Kit Customized Service Offer
n/a ELISA Kit for Benzisothiazolinone (BIT) ELISA Kit Customized Service Offer