Methandrostenolone (MD)

Methandrostenolone react strongly with the androgen receptor but still exerts its effects through the androgen receptor in vivo. These include dramatic increases in protein synthesis, glycogenolysis, and muscle strength over a short space of time. In high doses (50 mg ), side effects such as gynecomastia, high blood pressure, acne and male pattern baldness may begin to occur. The drug causes severe masculinising effects in women even at low doses. In addition, it is metabolized into methylestradiol by aromatase. This means that without the administration of aromatase inhibitors such as anastrozole or aminoglutethimide, estrogenic effects will appear over time in men. Many users will combat the estrogenic side effects with Arimidex, Nolvadex or Clomid. In addition, as with other 17α-alkylated steroids, the use of methandrostenolone over extended periods of time can result in liver damage without appropriate care.