Mesterolone (Mes)

Mesterolone is an orally applicable androgen, and DHT derivative. It is sold under the brand name Proviron (as Provironum in Asia-Pacific region), by Bayer Schering Pharma (earlier by Schering). In the late 70's and early 80's it was used with some success in controlled studies of men suffering from various forms of depression. Mesterolone is a relatively weak androgen and rarely used for replacement therapies.

Mesterolone had seen widespread use in bodybuilding primarily for antiestrogenic activity in anabolic steroid stacks but such use has declined after introduction of aromatase inhibitors and SERMs. Most significant benefits of current Mesterolone use are considered to be maintaining libido off-cycle and also relatively and temporarily improving vascularity.