Melanotan 1 (MTI)
Afamelanotide is a synthetic analog of the naturally occurring melanocortin peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that has been shown to induce skin pigmentation through melanogenesis and thereby subsequently reduce sun (UV) damage to UV exposed skin in preliminary studies and clinical trials. Its amino acid sequence is Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 or [Nle4, D-Phe7]-α-MSH. Afamelanotide is a non selective agonist of the melanocortin receptors (MC1R,MC3-5R). As an analogue of α-MSH, its mechanism of action is biomimicry of the natural mammalian tanning process. Afamelanotide produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Melanotan 1 (MTI) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanotan 1 (MTI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanotan 1 (MTI) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanotan 1 (MTI) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanotan 1 (MTI) ELISA Kit Customized Service Offer