Uperolein (Upe)
Uperolein, a physalaemin-like endecapeptide, has been shown to be selective for Neurokinin 1 receptor. The conformational range of the peptide revealed by NMR and CD studies has been analysed in terms of characteristic secondary features. Analysis of NMR data indicates that the global fold of Uperolein can be explained in terms of equilibrium between 310-helix and α-helix from residues 5 to 11.
An extended highly flexible N-terminus displays some degree of order and a possible turn structure. A comparison between the structures of Uperolein and Substance P, a prototype and endogenous Neurokinin 1 receptor agonist, indicates several common features in the distribution of hydrophobic and hydrophilic residues.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Uperolein (Upe) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Uperolein (Upe) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Uperolein (Upe) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Uperolein (Upe) CLIA Kit Customized Service Offer
n/a ELISA Kit for Uperolein (Upe) ELISA Kit Customized Service Offer