Palmitoyl pentapeptide is a five-sided molecule consisting of collagen fragment peptides lysine, threonine and serine, combined with palmitoyl, a fatty acid derivative of interferon-alpha. Both its high absorbability and fibroblast-stimulating property, clinical research shows, make palmitoyl pentapeptide an effective collagen booster. Increased collagen production reduces the appearance of wrinkles. Palmitoyl pentapeptide is now used in many anti-aging products. One of these peptides, pal-KTTKS or palmitoyl pentapeptide-3 (PP-3; recently renamed palmitoyl pentapeptide-4), is a ynthesized version of a protein fragment found in the most common type of collagen. It is a lipophilic modified peptide made of naturally derived amino acids. When PP3 is added to cultured human fibroblasts, it stimulates them to produce collagen, elastin, and hyaluronic acid, which are key components of the extracellular matrix.
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