Gramicidin A (GrA)
Gramicidin A, a hydrophobic linear polypeptide, forms channels in phospholipid membranes that are specific for monovalent cations. Nuclear Magnetic Resonance (NMR) spectroscopy provided the first direct physical evidence that the channel conformation in membranes is an amino terminal-to-amino terminal helical dimer, and circular dichroism (CD) spectroscopy has shown the sensitivity of its conformation to different environments and the structural consequences of ion binding. The three-dimensional structure of a gramicidin/cesium complex has been determined by x-ray diffraction of single crystals using single wavelength anomalous scattering for phasing. The left-handed double helix in this crystal form corresponds to one of the intermediates in the process of folding and insertion into membranes.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Gramicidin A (GrA) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Gramicidin A (GrA) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Gramicidin A (GrA) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Gramicidin A (GrA) CLIA Kit Customized Service Offer
n/a ELISA Kit for Gramicidin A (GrA) ELISA Kit Customized Service Offer