Activity Regulated Cytoskeleton Associated Protein (ARC)
[Edit]Arg3.1; Activity-regulated gene 3.1 protein homolog
The deduced 460-amino acid protein shares significant similarity with rat Arc. Northern blot analysis detected low ARC expression in heart, brain, lung, skeletal muscle, pancreas, prostate, and testis, weak expression in small intestine, colon, and peripheral blood leukocytes, and no expression in other tissues examined.Rat neurons express Arc at low levels under resting conditions, but Arc mRNA is rapidly induced and delivered into dendrites following synaptic activity. Arc assembled into particles that moved independently, bidirectionally, and intermittently with velocities consistent with both actin-based and microtubule-based transport. Rapidly translocating Arc mRNA particles sometimes reversed direction and decreased velocity just before stopping, suggesting that local signals regulate Arc mRNA targeting.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPJ620Hu01 | Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAJ620Hu01 | Polyclonal Antibody to Activity Regulated Cytoskeleton Associated Protein (ARC) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Activity Regulated Cytoskeleton Associated Protein (ARC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Activity Regulated Cytoskeleton Associated Protein (ARC) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPJ620Mu01 | Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPJ620Mu02 | Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAJ620Mu01 | Polyclonal Antibody to Activity Regulated Cytoskeleton Associated Protein (ARC) | WB; IHC; ICC; IP. |
PAJ620Mu02 | Polyclonal Antibody to Activity Regulated Cytoskeleton Associated Protein (ARC) | WB; IHC; ICC; IP. | |
Assay Kits | SEJ620Mu | ELISA Kit for Activity Regulated Cytoskeleton Associated Protein (ARC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPJ620Ra01 | Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAJ620Ra21 | Monoclonal Antibody to Activity Regulated Cytoskeleton Associated Protein (ARC) | WB; IHC; ICC; IP. |
PAJ620Ra01 | Polyclonal Antibody to Activity Regulated Cytoskeleton Associated Protein (ARC) | WB; IHC; ICC; IP. | |
Assay Kits | SEJ620Ra | ELISA Kit for Activity Regulated Cytoskeleton Associated Protein (ARC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy."Mol. Cell. Probes 14:255-260(2000) [PubMed] [Europe PMC] [Abstract].
- "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract].
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] and Uterus.
- "Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration."BMC Biol. 9:54-54(2011) [PubMed] [Europe PMC] [Abstract]