U251 cells are a commonly used human glioblastoma cell line that has been extensively studied in research laboratories. These cells were originally derived from a malignant brain tumor in a 72-year-old patient. U251 cells exhibit characteristics similar to those of glioblastoma, including rapid proliferation, invasiveness, and resistance to chemotherapy. Due to their cancerous nature, U251 cells are an important tool for studying the mechanisms of glioblastoma development and for testing potential therapeutic interventions. Researchers use U251 cells to better understand the biology of glioblastoma and to develop new treatments for this aggressive form of brain cancer.