PLC/PRF/5 Hepatocellular Carcinoma Alexander Cells (PLC/PRF/5)

PLC/PRF/5 cell line is a well-established human hepatocellular carcinoma cell line that has been widely used in research related to liver cancer and liver biology. The PLC/PRF/5 cell line was derived from a liver tumor specimen obtained from a 70-year-old Caucasian male patient with hepatocellular carcinoma.

PLC/PRF/5 cell line is characterized by its liver cancer origin and exhibits tumorigenic properties, making it a valuable tool for studying various aspects of liver cancer biology, including cell proliferation, migration, invasion, and response to therapeutic agents. Due to its tumorigenic nature, PLC/PRF/5 cells can be used to investigate tumor progression, metastasis, and the development of drug resistance in liver cancer.

Researchers commonly use the PLC/PRF/5 cell line to explore the molecular mechanisms underlying hepatocellular carcinoma pathogenesis, including genetic and epigenetic changes, aberrant signaling pathways, and interactions between tumor cells and the tumor microenvironment. By studying PLC/PRF/5 cells, scientists can identify potential biomarkers, therapeutic targets, and novel treatment strategies for liver cancer.