Kyse510 Esophageal Squamous Cell Carcinoma Cells (Kyse510)

KYSE-510 cell line is a well-established human esophageal squamous cell carcinoma (ESCC) cell line that has been widely used in cancer research, particularly in studies focused on esophageal cancer biology, tumor progression, and therapeutic interventions. KYSE-510 cells were originally derived from a primary tumor resected from a patient with esophageal cancer and have since served as a valuable model for investigating the molecular mechanisms underlying ESCC development and progression.

Esophageal squamous cell carcinoma is a major subtype of esophageal cancer, a highly aggressive malignancy with poor prognosis and limited treatment options. The KYSE-510 cell line represents a valuable tool for studying the pathogenesis of ESCC and exploring potential therapeutic strategies for combating this deadly disease.

KYSE-510 cells exhibit characteristics consistent with ESCC, including squamous morphology, high proliferation rate, and the ability to form tumors in xenograft models. Researchers often employ KYSE-510 cells to investigate various aspects of cancer biology, including cell signaling pathways, genetic mutations, metastatic potential, drug responsiveness, and resistance mechanisms.

Studies utilizing the KYSE-510 cell line have helped elucidate key molecular pathways involved in esophageal cancer progression, such as aberrant activation of signaling cascades (e.g., PI3K/Akt, MAPK), dysregulation of cell cycle checkpoints, and altered expression of oncogenes and tumor suppressor genes.