HCT15 Colon Carcinoma Cells (HCT15)

HCT15 cell line is another important human cell line derived from a colorectal adenocarcinoma, similar to the HCT8 and HT29 cell lines. HCT15 cells were established from the colon of a female patient with colorectal adenocarcinoma and have since been extensively studied for their relevance in cancer research.

HCT15 cells exhibit epithelial morphology and characteristics typical of colorectal cancer cells, similar to other colorectal adenocarcinoma-derived cell lines. They are capable of forming monolayers in culture and express markers associated with colorectal cancer, such as CEA and EpCAM. HCT15 cells are also responsive to various stimuli encountered in the tumor microenvironment, making them valuable tools for investigating colorectal cancer biology and treatment.

Researchers use HCT15 cells to explore key aspects of colorectal cancer, such as cell proliferation, invasion, metastasis, and drug response. The cell line's ability to replicate features of colorectal adenocarcinoma makes it a valuable model for studying the molecular mechanisms underlying cancer progression and identifying potential therapeutic targets.