Fadu Pharyngeal Squamous Carcinoma Cells (Fadu)

FaDu cells are a well-established and widely used human cell line derived from a hypopharyngeal squamous cell carcinoma. These cells were first isolated in the 1960s from a tumor in the pharynx of a 56-year-old male patient. FaDu cells have since become a popular model system for studying cancer biology, molecular signaling pathways, drug testing, and radiation therapy resistance in head and neck cancers.

FaDu cells are characterized by their epithelial morphology and aggressive cancerous behavior, making them a valuable tool for researchers investigating the underlying mechanisms of cancer progression and metastasis. These cells are known to exhibit high levels of invasiveness, migration, and resistance to standard cancer treatments, thereby providing a relevant model for studying tumor biology and therapeutic interventions in head and neck cancer.

Researchers often use FaDu cells to study various aspects of cancer biology, such as tumor growth, angiogenesis, apoptosis, and drug response. Their ability to form xenograft tumors in immunocompromised mice further extends their utility for in vivo studies of tumor behavior and therapeutic efficacy.