786-o Clear Cell Renal Cell Carcinoma Cells (786-o)

786-O cell line is a widely utilized human renal cell carcinoma cell line that was derived from a primary clear cell renal carcinoma tumor from a 58-year-old male patient. Renal cell carcinoma is the most common type of kidney cancer in adults, and the 786-O cell line serves as a valuable model for studying the biology of this disease and testing potential therapeutic interventions.

786-O cell line is characterized by its aggressive phenotype, including high proliferation rate, ability to form colonies in vitro, and resistance to conventional cancer treatments such as chemotherapy and radiation. These features closely mimic the behavior of renal cell carcinoma tumors in patients, making 786-O cells a relevant model for investigating the molecular mechanisms underlying the progression of this type of cancer.

Researchers use the 786-O cell line to explore various aspects of renal cell carcinoma biology, including cell signaling pathways, genetic mutations, and responses to different treatment modalities. By studying 786-O cells, scientists aim to uncover new insights into the mechanisms driving renal cell carcinoma progression and identify potential targets for the development of more effective therapies for this disease.