CNE-2Z Nasopharyngeal Carcinoma Cells (CNE-2Z)

CNE-2Z cell line is a widely used cell line derived from human nasopharyngeal carcinoma (NPC) cells. NPC is a type of cancer that originates in the nasopharynx, the upper part of the throat behind the nose. The CNE-2Z cell line was established from the parental CNE-2 cell line, which was originally derived from a poorly differentiated NPC biopsy.

CNE-2Z cells are characterized by their ability to grow rapidly in culture and to form tumors when injected into immunocompromised mice. These cells retain many characteristics of the original tumor, including the ability to secrete tumor markers and biomarkers associated with NPC. As a result, the CNE-2Z cell line has become a valuable tool for studying the biology and pathogenesis of NPC, as well as for screening potential therapeutic agents for the treatment of this cancer.

Researchers often use the CNE-2Z cell line to investigate various aspects of NPC, such as its molecular mechanisms, genetic alterations, signaling pathways, drug resistance, and metastasis. By studying these cells in vitro and in vivo, researchers can gain insights into the underlying mechanisms driving NPC progression and identify novel targets for therapeutic intervention.