BV2 Microglia Cells (BV2)

BV2 is a murine microglial cell line that is commonly used in research to study neuroinflammation and neurodegenerative diseases. These cells are derived from immortalized murine primary microglia and exhibit many characteristics of primary microglial cells, making them a valuable tool for studying the role of microglia in various neurological conditions.

BV2 cells express a range of microglial markers, such as CD11b and Iba1, and can be activated by pro-inflammatory cytokines and other immune signals.

Due to their ability to mimic primary microglia, BV2 cells have been used to study the mechanisms underlying neuroinflammation and neurodegeneration in diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Researchers can use BV2 cells to investigate the effects of different treatments or interventions on microglial function and inflammation, providing valuable insights into potential therapeutic strategies for these conditions.