BNL.1ME.A.7R.1 Hepatocytes (BNL.1ME.A.7R.1)

The BNL 1ME A.7R.1 cell line is a murine hepatocyte cell line that was established from the liver of a male C57BL/6 mouse. These cells were transformed and immortalized by transfection with an activated ras oncogene and exhibit features characteristic of malignant transformation. The BNL 1ME A.7R.1 cell line has been widely used in research to study liver biology, hepatocellular carcinoma, drug metabolism, and liver regeneration.

Researchers utilize the BNL 1ME A.7R.1 cell line to investigate various aspects of liver function, including metabolism, detoxification, and response to toxic compounds. Additionally, these cells have been employed to study the molecular mechanisms underlying liver cancer development and progression. The BNL 1ME A.7R.1 cell line serves as a valuable tool for understanding liver physiology and pathology, as well as for developing and testing new therapeutic strategies for liver diseases.