Endometrial cancer cell lines are critical tools to investigate the molecular mechanism of tumorigenesis using the end point cell-based assay such as proliferation, cytotoxicity, apoptosis, anoikis or migration and invasion. The proper assay optimization and performance is essential for physiologically relevant results interpretation. Profiling of cell lines by cell index measurement in proliferation and migration experiments was performed. The highest rate of proliferation was shown for Ishikawa cells. The rapid pace of cellular migration was observed in case of KLE and HEC-1-B cells as compared to weak migratory activity of Ishikawa cells. The cell index that reflects the cell status characterized real-time cytological profile of each analyzed cell line. These cell profiles were crucial for better planning the classical end-point assays used in further research.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Cells | CSI351Hu11 | Human HEC-1-B Endometrial Adenocarcinoma Cells (HEC-1-B) | HEC-1-B cell line serves as a valuable model system for studying endometrial cancer in vitro and has been instrumental in elucidating the molecular pathways involved in endometrial tumorigenesis. |
| Extracts | n/a | Extract of HEC-1-B Endometrial Adenocarcinoma Cells (HEC-1-B) | Total Protein/DNA/RNA Extract Customized Service Offer |
| Mediums | MSI351Hu11 | Medium for Human HEC-1-B Endometrial Adenocarcinoma Cells (HEC-1-B) | Complete Medium for the culture of HEC-1-B cell line |